Dengue
is the most common mosquito-related illness in humans. There are four serotypes
of the RNA flavivirus.
In
50 to 90% of individuals the infection is asymptomatic. Some, especially
children, experience a non-specific febrile illness. Classic Dengue Fever is
more common in non-immune, non-indigenous adults and children.
With
classic Dengue the infection often starts with chills, a red mottling of the
skin, and facial flushing, which is a sensitive and specific feature of Dengue
Fever. There is a rapid onset of high fever up to 41 degrees, headache,
retro-orbital pain, muscle and bone pain, weakness, vomiting, and sore throat.
Dengue fever is typically a self-limiting disease with a mortality rate of less
than 1%.
The rash begins
on day three and lasts 2 or 3 days. The rash is macular popular or macular
confluent and shows on the face, thorax, and flexor surfaces. The muscle pain
is prominent in the lower back, arms, and legs. The joint pain is usually in
the knees and shoulders.
A
small percentage of persons who have previously been infected by one dengue
serotype develop Dengue Hemorrhagic Fever (DHF) when infected with another
dengue serotype. DHF typical develops 3 to 7 days after infection with a second
dengue serotype. When treated, dengue hemorrhagic fever has a mortality rate of
2-5%, but when untreated, the mortality rate is as high as 50%.
Most cases are
self-limited and should be treated with analgesic, hydration, and rest. The
fever might last 5 to 7 days and recovery takes another 5 to 7 days.
Patients with
dengue fever should have their platelet count and hematocrit measured daily
from the third day of illness until 1-2 days after the fever resolves to look
for evidence of DHF.
I performed a Google Scholar search on Dengue in Haiti. Two
articles contained pertinent information.
2010 - A study of 166 children 7 to 36 months of age revealed
evidence of past infection with Dengue virus serotype 1 in
40%, serotype 2 in 12%, serotype 3 in 11%, and serotype 4 in 2%. Fifty-three
percent of infants and young children less than 12 months of age had already
experienced infection with a Dengue virus and by 36 months this rose to 65%.
2014 - A two-year prospective study in an
outpatient clinic in LĂ©ogane found that 2% of patients presenting with undifferentiated
fever tested positive for Dengue infection. Similarly, 4% of 885
patients with fever admitted to four hospitals in
Haiti during 2012–2013 tested positive for Dengue.
No comments:
Post a Comment